ANZGOG’s rare tumour, basket study, PARAGON-II, has officially opened to recruitment after activating its first site, Newcastle Private Hospital.
The trial, led by Medical Oncologist, Assoc Prof Chee Khoon Lee, seeks to improve outcomes for post-menopausal women with advanced (recurrent and/or metastatic) gynaecological cancers, that are hormone-receptor-positive. The study follows on from PARAGON, an ANZGOG trial that pioneered a unique and novel clinical trial design – the ‘basket’ trial – to facilitate the recruitment of patients with rare tumours, within a single trial.
What is a ‘basket’ study?
A basket study is a study that tests how a new treatment works in patients who have different types of cancer that all have the same mutation or biomarker.
Who is eligible to participate?
Women may be eligible for this study if they are aged 18 or older, with advanced (recurrent and/or metastatic) gynaecological cancers, that are hormone-receptor positive. More information on eligibility can be found on ANZGOG’s Clinical Trials page. Patients are encouraged to speak with their oncologist regarding their concerns including the best ways for their participation on a clinical trial.
Where will the study take place?
The study plans to open at least 15 sites in ANZ, with a target of recruiting 182 participants. Planned sites include:
- Newcastle Private Hospital, NSW
- Monash Medical Centre, VIC
- Border Medical Oncology and Research Unit, NSW
- Prince of Wales Hospital / Royal Hospital for Women, NSW
- Westmead Hospital, NSW
- Peter MacCallum Cancer Centre, VIC
- Mater Cancer Care Centre, QLD
- Sir Charles Gairdner Hospital, WA
- Royal North Shore Hospital, NSW
- Royal Brisbane and Women’s Hospital, QLD
- St George Hospital, NSW
- Auckland City Hospital, NZ
- Wollongong Hospital, NSW
- Royal Hobart Hospital, TAS
- Canberra Hospital, ACT
Watch Assoc Prof Chee Lee explain the PARAGON-II study in the video below:
Want to know more about ANZGOG’s clinical trials?
To find out more about ANZGOG’s clinical trials, click here. Please always speak to your oncologist if you are interested in participating in a trial.